Caffeine is a white crystaline powder used primarily as a stimulate in the consumption of beverages and food. It is also found in prescription medications.
Main applications of Caffeine
Used mainly in soft drinks, energy drinks, dietary supplments, beverages, pharmacalogical agent, inhalant supplement, protein bars, hot chocolate and breakfast cereals.
Soft Drinks
Energy Drinks
Beverages
Dietary Supplments
Inhalant Supplement
Pharmacalogical Agent
Protein Bars
Hot Chocolate
Breakfast Cereals
Specification of Caffeine
Identification
Synonims
1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione
Chemical formula
Formula: C8H10N4O2
Molecular weight: 194.2
Identification numbers
CAS number: 58-08-2
Mesh
>95% through 40 mesh
>95% through 80 mesh
Physical properties
Appearance: White or almost white, crystalline powder or silky, white or almost white, crystals.
Solubility: Sparingly soluble in water, freely soluble in boiling water, slightly soluble in ethanol (96 percent). It dissolves in concentrated solutions of alkali benzoates or salicylates.
Compendial Requirements
Caffeine meets all requirements of EP8.0, BP2014, USP37, FCC8, when tested according to these compendia.
Identification (FCC)
Chemical reaction: Positive reaction
Infrared absorption: Conforms to the caffeine Reference Spectrum
Test
Appearance of solution: Clear, colorless (EP/BP)
Heavy metals: ≤10ppm (USP)
Sulphates: ≤500ppm（EP/BP）
Acidity: Not more than 0.2ml of 0.01M sodium hydroxide（EP/BP）
Organic impurities: Any individual impurity ≤0.1% (USP)
Organic impurities: Total impurities ≤0.1% (USP)
Related substances: Each impurity A, B, C, D, E, F ≤0.10% （EP/BP）
Related substances: Each unspecified impurity ≤0.10% （EP/BP）
Related substances: Total impurities ≤0.1% （EP/BP）
Lead: ≤1mg/kg (FCC)
Other alkaloids: No precipitation generated (FCC)
Melting point: 235ºC~237.5ºC (FCC)
Readily carbonizable substances: Conform to the requirement (FCC)
Loss on drying: ≤0.5%(EP/BP)
Sulphate ash: ≤0.1%(USP)
Assay
98.5～101.0% (USP)
Handling - Storage
Keep in a tightly closed container,stored in a natural temperature ,ventilated area.
Protect against physical damage. Containers of this material may be hazardous when empty since they retain product residues (dust ,solids);
observe all warnings and precautions listed for the product.
Format and presentation
PACKAGED FORM
Carton: 1×20kg
Documents of Caffeine
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